European Cardiology Review (ECR)  is a peer-reviewed bi-annual journal comprising review articles, editorials and case reports. It features balanced and comprehensive articles written by leading authorities, addressing the most important and salient developments in cardiovascular medicine and practice.

Led by Editor-in-Chief Juan Carlos Kaski, supported by Associate Editors, and underpinned by an editorial board of world-renowned physicians, ECR is comprised of peer-reviewed articles that aim to provide timely updates on the most pertinent cardiology issues.

For information on submitting an article, please contact the Managing Editor, Lindsey Mathews: commeditor@radcliffecardiology.com

Effect of Percutaneous Coronary Intervention on Heart Rate Variability in Coronary Artery Disease Patients

Author : Mahmoud H Abdelnaby

Citation :

European Cardiology Review 2018;13(1):60–1.

Overview:Coronary artery disease (CAD) is the most common cause of morbidity and premature mortality globally,1 and cardiac autonomic... more

The Newest Generation of Drug-eluting Stents and Beyond

Author : Dae-Hyun Lee, Jose M de la Torre Hernandez

Citation :

European Cardiology Review 2018;13(1):54–9.

Overview:When Andreas Grüntzig introduced balloon coronary angioplasty in 1977 it represented the first alternative to coronary artery bypass graft surgery. However, balloon dilatation... more

Assessing the Haemodynamic Impact of Coronary Artery Stenoses: Intracoronary Flow Versus Pressure Measurements

Author : Valérie E Stegehuis, Gilbert WM Wijntjens, Tadashi Murai, Jan J Piek, Tim P van de Hoef

Citation :

European Cardiology Review 2018;13(1):46–53.

Overview:The emphasis in ischaemic heart disease (IHD) diagnosis has historically been directed towards the identification of epicardial coronary stenosis by selective coronary... more

Role of Anti-inflammatory Interventions in Coronary Artery Disease: Understanding the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS)

Author : Alberto Lorenzatti, Maria Luz Servato

Citation :

European Cardiology Review 2018;13(1):38–41.

Overview:Coronary artery disease (CAD) is the leading cause of death in most countries. Compelling evidence from epidemiological, genetic and clinical studies as well as experiments in... more

Neuroendocrine System Regulatory Mechanisms: Acute Coronary Syndrome and Stress Hyperglycaemia

Author : Ricardo A Perez de la Hoz, Sandra Patricia Swieszkowski, Federico Matias Cintora, Jose Martin Aladio, Claudia Mariana Papini, Maia Matsudo, Alejandra Silvia Scazziota

Citation :

European Cardiology Review 2018;13(1):29–34.

Overview:The aim of reviewing the neuroendocrine–humoral response in acute coronary syndrome (ACS) is based on the fact that beyond the distinctive thrombotic event that defines acute... more

Nicorandil and Long-acting Nitrates: Vasodilator Therapies for the Management of Chronic Stable Angina Pectoris

Author : Jason M Tarkin, Juan Carlos Kaski

Citation :

European Cardiology Review 2018;13(1):23–8.

Overview:Stable angina pectoris is the most prevalent clinical manifestation of coronary heart disease. While the overall prognosis in patients with stable angina is good, with a low... more

Familial Hypercholesterolaemia Diagnosis and Management

Author : Rodrigo Alonso, Leopoldo Perez de Isla, Ovidio Muñiz-Grijalvo, Jose Luis Diaz-Diaz, Pedro Mata

Citation :

European Cardiology Review 2018;13(1):14–20.

Overview:Familial hypercholesterolaemia (FH) is the genetic disorder most commonly associated with elevated LDL cholesterol (LDL-C) levels from birth and with premature atherosclerotic... more

Management of Severe Dyslipidaemia: Role of PCSK9 Inhibitors

Author : Stephen J Nicholls

Citation :

European Cardiology Review 2018;13(1):9–13.

Overview:Therapeutic targeting of dyslipidaemia has been one of the major successes in cardiovascular medicine over the last three decades. On the basis of unequivocal evidence from... more

Cardiovascular Implications of Sphingomyelin Presence in Biological Membranes

Author : Petros Kikas, George Chalikias, Dimitrios Tziakas

Citation :

European Cardiology Review 2018;13(1):42–5.

Overview:Sphingolipids are one of the major categories of lipids and beyond their role as structural membrane components they have important functions as signalling molecules in a wide... more

Cardio-oncology: A Focus on Cardiotoxicity

Author : Athanasios Koutsoukis, Argyrios Ntalianis, Evangelos Repasos, Efsthathios Kastritis, Meletios-Athanasios Dimopoulos, Ioannis Paraskevaidis

Citation :

European Cardiology Review 2018;13(1):64–9.

Overview:Cardio-oncology is an emerging field of cardiology that focuses on cardiovascular diseases in patients with cancer. The classic cardio-oncology paradigm is the prevention,... more