2020 ISCP Annual Meeting cancelled

February 26 ,2020

Overview:Notice of Cancellation We regret to have to inform our colleagues and friends that the 2020 ISCP Annual Scientific Meeting in Miami will now be cancelled. The Board of Directors of ISCP was forced to take the decision based on advice from different sources raising concern about the threat posed by the Covid-19 virus which […] more

CVD tied to highest mortality rate vs. other causes of dizziness

April 02 ,2020

Overview:Patients with CVD-related dizziness had a higher mortality rate than those whose dizziness was primarily caused by peripheral vestibular disease, according to a prospective cohort study published in Annals of Family Medicine.Researchers also found that dizziness-related impairment in older patients was common 10 years after their diagnosis.The first finding is “novel because this is the first study on differences of mortality in dizziness,” Vincent A. van Vugt, MD, from the department of general practice and elderly care medicine at Amsterdam Public Health in the Netherlands, told more

Rivaroxaban superior to enoxaparin for VTE prevention after nonmajor orthopedic surgery

April 02 ,2020

Overview:Treatment with rivaroxaban was more effective than enoxaparin for preventing venous thromboembolism during immobilization after lower-limb nonmajor orthopedic surgery, according to results of the PRONOMOS trial.Among 3,604 patients randomly assigned to oral rivaroxaban (Xarelto, Janssen/Bayer) or subcutaneous enoxaparin, major VTE occurred in 0.2% of the rivaroxaban group compared with 1.1% of the enoxaparin group (RR = 0.25; 95% CI, 0.09-0.75; P < .001 for noninferiority; P = .01 for superiority), according to data presented at the virtual American College of Cardiology Scientific more

Chronic exercise training increases fatty acid, ketone consumption in men

April 02 ,2020

Overview:The extent and magnitude of metabolic adaptation to chronic exercise training in men were greater than originally believed, likely due to increased consumption of ketone body substrates and fatty acid, researchers reported in Cardiovascular Research.“These results show that metabolic adaptation to exercise is far more profound than previously reported,” John O’Sullivan, MD, clinical-academic cardiologist at the University of Sydney and the Royal Prince Alfred Hospital, said in a press release. “The results increase our knowledge of the widespread benefits of exercise more

Top cardiology news in March: COVID-19 and the heart, plant-based benefit and more

April 02 ,2020

Overview:Healio and Cardiology Today have compiled a list of the most-read news published in March.Healio readers were most interested in news about COVID-19, particularly CVD considerations of the virus; new research from the American Heart Association Epidemiology, Prevention, Lifestyle and Cardiometabolic Health Scientific Sessions; and more.See below for Healio’s highlights from March. Cardiology societies recommend patients taking ACE inhibitors, ARBs who contract COVID-19 should continue treatmentSeveral American and European cardiology societies issued statements to dispel more

Preeclampsia during pregnancy increases risk for neurodevelopmental disorders among offspring

April 02 ,2020

Overview:Preeclampsia in term pregnancies appeared to have lasting effects on the neurodevelopment of the child, according to results of a prospective, population-based cohort study published in JAMA Psychiatry.“Term preeclampsia is usually a mild condition, and we usually regard it as of no consequence to the health of the baby,” Allen J. Wilcox, MD, PhD, head of the reproductive epidemiology group at the National Institute of Environmental Health Sciences, told Healio Psychiatry. “Our results suggest that something about the pathology of preeclampsia may contribute to a more

Clinical review of COVID-19 and CVD: What the cardiovascular practitioner needs to know

April 01 ,2020

Overview:by Eamon Duffy, MD, MBA; Andrew Ayers; Miguel Caínzos-Achirica, MD, MPH, PhD; and Roger S. Blumenthal, MDThe novel coronavirus disease, or COVID-19, is now a global pandemic. Clinicians, scientists and public health officials around the world are racing to define the molecular pathway and clinical presentation of the virus, identify risk factors for infection and poor clinical outcomes, and develop effective treatments and preventive interventions.Although the data on each of these ventures continue to develop on a daily basis across the globe, several trends have emerged showing that more

Q&A: COVID-19 disrupts 2020 census

April 01 ,2020

Overview:The negative downstream effects of the COVID-19 pandemic may extend to the United States census, a business and economy expert told Healio Primary Care.“It’s still too early to say, but I will not be surprised if the Census Bureau ends up pushing back the date of releasing the results,” said Christiadi, PhD, research associate at the John Chambers College of Business and Economics at West Virginia University.Christiadi discussed how COVID-19 is impacting the decennial survey, the populations that will be affected most by the census disruption, and more. – by Janel more

Prognosis of patients with ischemia, nonobstructive CAD can change over time

March 31 ,2020

Overview:In the CIAO ancillary study of patients who were screened for the ISCHEMIA trials but were excluded because they had ischemia but no obstructive CAD, stress echocardiography results and angina frequency changed over time, researchers reported at the virtual American College of Cardiology Scientific Session.In addition, there was no correlation between change in ischemia and change in angina at 1 year in patients with ischemia but no obstructive CAD (INOCA) on coronary CT angiography, Harmony R. Reynolds, MD, associate professor of medicine and associate director of the Cardiovascular Clinical more

Edoxaban noninferior to warfarin for thromboembolism, bleeding early after surgical valve implantation or repair

March 31 ,2020

Overview:In patients who underwent surgical bioprosthetic valve implantation or repair, early postoperative anticoagulation with edoxaban was noninferior to warfarin for preventing thromboembolism and major bleeding during the first 3 months after the procedure, according to results of the ENAVLE trial presented at the virtual American College of Cardiology Scientific Session.“Our findings suggest edoxaban might be an alternative to warfarin in patients early after successful surgical bioprosthetic valve implantation or valve repair,” Geu-Ru Hong, MD, PhD, professor in the division of more

Certain medical devices with FDA priority review have higher recall rates

March 31 ,2020

Overview:High-risk, or class 3, medical devices that underwent FDA priority review had higher recall rates and less time on the market before serious recalls vs. high-risk devices that received standard review, data published in JAMA Internal Medicine showed.“The FDA requires that high-risk (class 3) medical devices undergo premarket approval review, the most stringent path through which devices enter the market,” Caroling Ong, MD, MHS, first-year cardiology fellow in the division of cardiology at NYU Grossman School of Medicine, and colleagues wrote. “Since 1994, in an effort to more

Higher temperatures may increase heart disease mortality risk

March 31 ,2020

Overview:In a new study, researchers reported that higher ambient temperatures as observed in Kuwait may be associated with higher CVD mortality.“We were surprised by the scale of effects that extremely hot temperatures can have on cardiovascular mortality in hot and hyper-arid regions,” Barrak Alahmad, MBChB, MPH, mission scholar from Kuwait University and a PhD candidate in environmental health at the Harvard T.H. Chan School of Public Health, told Healio. “We found that the risks of cardiovascular death in Kuwait at extreme high temperatures were remarkably high, with a doubling more

Alirocumab, evinacumab confer LDL benefit in homozygous familial hypercholesterolemia

March 30 ,2020

Overview:Two studies presented at the virtual American College of Cardiology Scientific Session highlight new options for LDL cholesterol reduction in patients with homozygous familial hypercholesterolemia.In the ODYSSEY HoFH study, the PCSK9 inhibitor alirocumab (Praluent, Sanofi/Regeneron) reduced LDL cholesterol by 35.6% compared with placebo in adults with homozygous familial hypercholesterolemia (HoFH). In a second study, the investigational therapy evinacumab (Regeneron), a monoclonal antibody that bins to ANGPTL3, reduced cholesterol to near-normal levels in this population.“There have more

Nicotine e-cigarettes, counseling aid smoking cessation in randomized trial

March 30 ,2020

Overview:At 12 weeks, nicotine e-cigarettes combined with individual counseling was more effective for smoking cessation than non-nicotine e-cigarettes plus counseling or counseling alone, results from the E3 trial showed.During the study period, several adverse events occurred but were adjudicated by an endpoint evaluation committee as unrelated to the treatments.According to research from the 376-participant trial presented at the virtual American College of Cardiology Scientific Session, participants randomly assigned to combination nicotine e-cigarettes and counseling therapy for smoking cessation more

Mavacamten shows promise in nonobstructive hypertrophic cardiomyopathy

March 30 ,2020

Overview:In patients with nonobstructive hypertrophic cardiomyopathy, treatment with mavacamten was well tolerated and reduced biomarkers of cardiac injury and wall stress, according to results of the phase 2 MAVERICK-HCM study.MAVERICK-HCM is “the first study to show an improvement in serum biomarkers of hemodynamic stress and myocardial injury in patients with nonobstructive [hypertrophic cardiomyopathy],” Carolyn Y. Ho, MD, medical director of the cardiovascular genetics center at Brigham and Women’s Hospital and associate professor at Harvard Medical School, said during a virtual more

NT pro-BNP predicts events, is lowered by sacubitril/valsartan in HFpEF

March 30 ,2020

Overview:Baseline N-terminal pro-B natriuretic peptide in patients with HF with preserved ejection fraction accurately predicted HF hospitalizations and CV death, according to an analysis of the PARAGON-HF trial.In addition, sacubitril/valsartan (Entresto, Novartis) successfully lowered NT pro-BNP over 16 weeks post-randomization, with similar reductions in both men and women and across the range of LV ejection fraction.As Healio previously reported, in PARAGON-HF, sacubitril/valsartan did not significantly improve clinical outcomes in the overall cohort, but women were more likely to benefit from the more

No difference in cardiac, cerebrovascular events with left main PCI vs. CABG at 10 years: PRECOMBAT

March 30 ,2020

Overview:Ten-year extended follow-up of the PRECOMBAT trial demonstrates no difference in the incidence of major adverse cardiac or cerebrovascular events regardless of whether patients with unprotected left main CAD were treated with PCI with a first-generation drug-eluting stent or CABG.However, the rate of ischemia-driven target vessel revascularization at 10 years was higher among patients who underwent PCI.The results are relevant, as “data are still limited on very long-term — beyond 5 years — outcomes of PCI or CABG in patients with left main coronary artery disease [and] more

Ticagrelor monotherapy beneficial in complex PCI, diabetes: New TWILIGHT data

March 30 ,2020

Overview:In new findings from the TWILIGHT trial of patients who underwent PCI, switching from dual antiplatelet therapy to ticagrelor monotherapy after 3 months benefited patients who had complex PCI and patients with diabetes.As Healio previously reported, in the main results of TWILIGHT, among patients who underwent PCI with a drug-eluting stent and were on ticagrelor (Brilinta, AstraZeneca) plus aspirin for 3 months, those who switched to ticagrelor monotherapy had reduced risk for Bleeding Academic Research Consortium (BARC) type 2, 3 or 5 bleeding at 1 year compared with those who stayed on more

ACC.20/WCC Virtual: WHF President Prof Karen Sliwa Opening Remarks

March 30 ,2020

Overview:Dear friends, Thank you for contributing to the most important discussion about heart health in the world. As we get ready to delve into a new form of our joint Congress, I would like to pay a special tribute to those who are in the front lines of what is an unprecedented struggle with a […] The post ACC.20/WCC Virtual: WHF President Prof Karen Sliwa Opening Remarks appeared first on World Heart Federation. more

WHF and IASC launch new Global Roadmap to eliminate Chagas disease

March 30 ,2020

Overview:WASHINGTON, D.C./GENEVA (30 March 2020) – The World Heart Federation (WHF) launched today a new roadmap aimed at reducing the global burden of Chagas disease. Currently, an estimated 75 million people are at risk of acquiring Chagas – a Neglected Tropical Disease which can cause irreversible damage to the heart and other vital organs. Chagas […] The post WHF and IASC launch new Global Roadmap to eliminate Chagas disease appeared first on World Heart Federation. more

Sodium nitrite confers no survival benefit in out-of-hospital cardiac arrest

March 29 ,2020

Overview:IV sodium nitrite administered by paramedics for out-of-hospital cardiac arrest had no effect on survival to hospital admission or discharge compared with placebo, according to data presented at the virtual American College of Cardiology Scientific Session.Moreover, sodium nitrite showed no significant adverse effects on patient hemodynamics compared with placebo.For this double-blind randomized trial, 1,492 unconscious adult patients with out-of-hospital cardiac arrest were administered IV sodium nitrite (45 mg or 60 mg) or placebo by paramedics approximately 22 minutes from initial call. more

New insights on low-risk TAVR vs. surgery: PARTNER 3 at 2 years

March 29 ,2020

Overview:In a population of patients with severe symptomatic aortic stenosis at low surgical risk, TAVR using a balloon-expandable valve compared with surgery at 2 years yielded a 37% reduction in death, stroke or CV rehospitalization, but more death, stroke and increased valve thrombosis events occurred from 1 to 2 years among patients who underwent TAVR, according to new data from the PARTNER 3 trial.As Healio previously reported, PARTNER 3, which enrolled 1,000 patients with severe aortic stenosis and a mean Society of Thoracic Surgeons Predicted Risk Of Mortality score of 1.9%, was presented at more

Oral anticoagulation alone reduces bleeding after TAVR vs. dual therapy

March 29 ,2020

Overview:The incidence of serious bleeding after transcatheter aortic valve replacement was lower in patients assigned oral anticoagulation alone compared with those assigned oral anticoagulation and clopidogrel, according to data from the POPULAR-TAVI trial presented at the American College of Cardiology Scientific Session.The findings were simultaneously published in The New England Journal of Medicine.“Oral anticoagulants alone as compared to oral anticoagulants with clopidogrel reduces the rate of bleeding events including major, life-threatening or disabling bleeding, and it does not more

Call for papers: submit your research on COVID-19 and CVD

March 20 ,2020

Overview:The world is struck by the COVID-19 pandemic. While the eventual spread remains uncertain, as is the true case-fatality rate, research shows that older patients with chronic cardiovascular conditions are particularly vulnerable. The infection puts pressure on health systems and staff both through health professionals being affected or quarantined and depletion of hospital resources and […] The post Call for papers: submit your research on COVID-19 and CVD appeared first on World Heart Federation. more

WHF President Prof Karen Sliwa’s message on COVID-19

March 20 ,2020

Overview:19 March 2020 Dear Members and friends, We are going through a global health crisis, which is unprecedented in our lifetime. Many lives are being lost each day and the virus continues to spread everywhere in the world. We are, however, encouraged that our colleagues from China – the first and worst hit country so […] The post WHF President Prof Karen Sliwa’s message on COVID-19 appeared first on World Heart Federation. more

ACC.20/WCC goes virtual!

March 16 ,2020

Overview:Last week, we had to take the difficult decision to cancel ACC.20/WCC in Chicago. This was absolutely the right decision given the need for cardiovascular clinicians around the world to be on the front lines helping patients and their communities address COVID-19. Since then, the ACC.20/WCC team has been hard at work creating a virtual […] The post ACC.20/WCC goes virtual! appeared first on World Heart Federation. more

ACC.20/WCC in Chicago has been cancelled

March 09 ,2020

Overview:After careful consideration, the difficult decision has been made to cancel the ACC’s Scientific Session Together with World Congress of Cardiology (ACC.20/WCC) scheduled to take place March 28-30, 2020 in Chicago. The decision to cancel this important event was not taken lightly. WHF and ACC have been closely monitoring updates and recommendations from the Centers […] The post ACC.20/WCC in Chicago has been cancelled appeared first on World Heart Federation. more

Celebrating 15 years of the Framework Convention on Tobacco Control

March 06 ,2020

Overview:Yesterday the world marked the 15th anniversary of the entry into force of the WHO Framework Convention on Tobacco Control (FCTC). The FCTC remains the first and only international treaty on public health negotiated under the auspices of World Health Organization. It was adopted by the World Health Assembly on 21 May 2003. It has […] The post Celebrating 15 years of the Framework Convention on Tobacco Control appeared first on World Heart Federation. more

Preventing COVID-19 spread in poor areas

March 05 ,2020

Overview:5 March 2020, Geneva/Cape Town The novel coronavirus (COVID-19) epidemic started late December in Wuhan City, Hubei Province, China, and has since spread to 87 countries and territories in the world. Poor regions haven’t been spared and the need for a context-specific response has become urgent. Large and densely populated areas with widespread poverty and […] The post Preventing COVID-19 spread in poor areas appeared first on World Heart Federation. more

Tiny Hearts of Maldives pilot new physical activity programme for schoolchildren

February 20 ,2020

Overview:In September 2019, Tiny Hearts of Maldives piloted a physical activity circuit for children in kindergarten and Grades 1 to 2 in a school of Male’ City. The Activity Circuit, which encourages sitting less and moving more, comprises of attractive, child friendly designs installed along a school corridor that takes the children on a quick […] The post Tiny Hearts of Maldives pilot new physical activity programme for schoolchildren appeared first on World Heart Federation. more

Increasing awareness of the cardiovascular consequences of obesity

February 20 ,2020

Overview:The World Heart Federation (WHF) and the World Obesity Federation (WOF) have joined forces to highlight the importance of recognizing obesity as one of the main drivers of cardiovascular disease (CVD). To kick off the collaboration, a meeting of experts was convened in Paris during the European Society of Cardiology together with the World Congress […] The post Increasing awareness of the cardiovascular consequences of obesity appeared first on World Heart Federation. more

European Cardiology Review (ECR) now on PubMed and PubMed Central

October 30 ,2018

Overview:    European Cardiology Review (ECR) confirms that it has been accepted for indexing on PubMed Central and PubMed. All ECR articles starting from the first issue in July 2014, will now be published online in full on PubMed Central, providing greater access for our authors’ articles amongst the global cardiology community. ECR is a […] more

WHF to attend the WHO Executive Board meeting in January 2017

January 23 ,2017

Overview:From 23 January to 01 February 2017, the World Health Organization(WHO) will host the 140th session. From 23 January to 01 February 2017, the World Health Organization(WHO) will host the 140th session. From 23 January to 01 February 2017, the World Health Organization(WHO) will host the 140th session. From 23 January to 01 February 2017, […] more