CVD, diabetes in HBV linked to chronic kidney disease risk
September 25 ,2018
Overview:A review of adults with chronic hepatitis B who had continuous medical coverage showed that the presence of extrahepatic comorbidities such as hypertension, cardiovascular disease and diabetes were among the primary risks for chronic kidney disease.“Understanding the care of clinically complex [chronic HBV (CHB)] patients is especially relevant since the rate of screening, diagnosis, and linkage to care for CHB patients is poor,” Mindie H. Nguyen, MD, MAS, AGAF, FAASLD, from the Stanford University Medical Center in California, and colleagues wrote. “Due to this more
Renal denervation superior to ablation in resistant hypertension
September 25 ,2018
Overview:SAN DIEGO — Endovascular ultrasound-based renal sympathetic denervation in patients with resistant hypertension was superior to radiofrequency ablation of the main renal arteries, according to data from the RADIOSOUND-HTN trial presented at TCT 2018.In contrast, a combined approach of radiofrequency ablation of the main arteries, side branches and accessories was not superior to endovascular ultrasound-based renal sympathetic denervation.“This pilot study precludes definite recommendations regarding the preferable renal denervation approach,” Philipp Lurz, MD, PhD, chief more
VIDEO: Ajay Kirtane, MD, SM, shares highlights from TCT 2018
September 25 ,2018
Overview:SAN DIEGO — In this video exclusive, Ajay Kirtane, MD, SM, provides insight on the COAPT trial, the 30th anniversary of TCT and other highlights from TCT.This year marks the 30th anniversary of the TCT meeting, which began with a few hundred people in Washington, D.C., and has since expanded greatly, in terms of attendance and excitement, Kirtane, who is a co-director of TCT and also a physician at NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, told Cardiology Today’s Intervention. Also this year, TCT featured Interactive Training Workshops that offered more
Severe prosthesis-patient mismatch portends risk after TAVR
September 25 ,2018
Overview:Howard C. HerrmannSAN DIEGO — Severe prosthesis-patient mismatch conferred elevated risk for mortality and HF hospitalization at 1 year after transcatheter aortic valve replacement, according to a presentation at TCT 2018.Howard C. Herrmann, MD, director of the cardiac catheterization laboratories and health system director for interventional cardiology at the Hospital of the University of Pennsylvania and John Winthrop Bryfogle Professor of Cardiovascular Diseases at the Perelman School of Medicine at the University of Pennsylvania, and colleagues analyzed 62,125 patients (mean age, 81 more
BIOFLOW V: Bioresorbable polymer DES reduces risk for TLR, target vessel MI
September 25 ,2018
Overview:David E. KandzariSAN DIEGO — Patients with non-STEMI and ACS who underwent PCI with an ultrathin, bioresorbable polymer sirolimus-eluting stent had reduced risk for target lesion failure and target vessel MI compared with patients assigned a thin, durable polymer everolimus-eluting stent, according to 2-year data from the BIOFLOW V trial.Those assigned the SES (Orsiro, Biotronik) also had a lower rate of target lesion revascularization vs. the EES (Xience, Abbott Vascular).“This was the first time in a large comparative randomized trial that we observed a significant difference more
Young, fit athletes still carry CVD risk
September 25 ,2018
Overview:Barbara N. MorrisonResearchers found that 11% of “master” athletes had CVD, according to a study recently published in BMJ Open Sport & Exercise Medicine.“I noticed that young, fit individuals were having heart attacks and I wanted to know why,” Barbara N. Morrison, PhD student in experimental medicine at the University of British Columbia in Canada, told Healio Family Medicine.Researchers performed preparticipation screening on 798 master athletes who had engaged in moderate to vigorous intensity physical activity at least 3 days per week during the previous 3 more
Countdown to World Heart Day
September 25 ,2018
Overview:With World Heart Day just a few days away, now’s the time to create your own poster, download the toolkit, watch the video … and more. Here are all the ways you can support our My Heart, Your Heart campaign and help to spread the word about heart-healthy lifestyles: Watch the campaign video Create, download […] The post Countdown to World Heart Day appeared first on World Heart Federation. more
ULTIMATE: IVUS guidance bests angiography guidance in 12-month outcomes after PCI
September 25 ,2018
Overview:SAN DIEGO — Patients who underwent drug-eluting stent implantation with IVUS guidance had improved 12-month clinical outcomes compared with those who underwent implantation with angiography guidance, according to data from the ULTIMATE trial presented at TCT 2018.Jun-Jie Zhang, PhD, MD, vice director of the cardiovascular department at Nanjing First Hospital at Nanjing Medical University in China, and colleagues analyzed data from an all-comer population of 1,448 patients with silent ischemia, MI or stable or unstable angina more than 24 hours from the onset of chest pain to hospital more
MAIN-COMPARE: Outcomes similar in CABG, PCI for left main CAD
September 24 ,2018
Overview:SAN DIEGO — Patients with significant left main CAD who underwent PCI had similar rates of death and a composite outcome up to 10 years compared with those who underwent CABG, according to data from the MAIN-COMPARE registry presented at TCT 2018.PCI conferred increased rates of target vessel revascularization in the overall cohort, whereas among those whose procedures occurred in the drug-eluting stent era, CABG resulted in reduced risk for mortality and serious composite outcomes after 5 years.“The treatment benefit of CABG has diverged over time during continued follow-up,” more
Long-term oral anticoagulation alone not sufficient in AF, CAD after stenting
September 24 ,2018
Overview:SAN DIEGO — Noninferiority was not established for oral anticoagulation alone vs. oral anticoagulation with antiplatelet therapy in patients with atrial fibrillation and stable CAD more than 1 year after stenting, according to data from the OAC-ALONE study presented at TCT 2018.Yukiko Matsumura-Nakano, MD, PhD candidate in the department of cardiovascular medicine at Kyoto University Graduate School of Medicine in Japan, and colleagues performed an intention-to-treat analysis on data from 690 patients (mean age, 75 years; 85% men; mean CHA2DS2-VASc score, 4.6) with concomitant AF and more
Benefit of anticoagulation for atrial fibrillation varies across patient populations
September 24 ,2018
Overview:When using current guideline recommendations, the clinical net benefit of starting oral anticoagulation varied widely among patients with atrial fibrillation, according to findings published in Annals of Internal Medicine.Using anticoagulation in a patient with a CHA2DS2-VASc (congestive heart failure, hypertension, age, diabetes, stroke and vascular disease) score of 2 or higher is currently recommended by guidelines, according to Sachin J. Shah, MD, MPH, from the University of California, San Francisco, and colleagues.However, “stroke rates in patients with nonvalvular atrial more
Positive CV results reported for dapagliflozin
September 24 ,2018
Overview:Results from the phase 3 DECLARE-TIMI 58 cardiovascular outcomes trial confirmed the safety of dapagliflozin, according to a press release from AstraZeneca.In addition, the SGLT2 inhibitor met one of its two primary efficacy endpoints of a statistically significant reduction in hospitalization for heart failure or CV death, according to the release.The results demonstrated noninferiority of dapagliflozin (Farxiga, AstraZeneca) to placebo when added to background diabetes therapies for the primary safety endpoint of major adverse CV events. Although the agent was associated with a reduction in more
Peripheral DES receives FDA approval
September 24 ,2018
Overview:William A. GrayBoston Scientific announced that the FDA has approved its drug-eluting stent with a polymer coating for treatment of peripheral artery disease.The device (Eluvia, Boston Scientific) is the second DES approved in the U.S. to treat PAD. The approval was based upon the results of the IMPERIAL trial, in which the Eluvia device was superior to the other device approved for the indication, a DES without a polymer coating (Zilver PTX, Cook Medical) in patency and target lesion revascularization at 12 months, according to a press release from Boston Scientific.The IMPERIAL trial also more
REDUCE-IT topline results announced: Icosapent ethyl reduces CV events
September 24 ,2018
Overview:Norman E. LeporAmarin announced today topline results from the REDUCE-IT CV outcomes trial showing that the trial met its primary endpoint demonstrating approximately 25% RR reduction in major adverse CV events in the intent-to-treat population with use of icosapent ethyl compared with placebo.“The composite cardiovascular event reduction of 25% with a very high level of statistical significance is a game changer,” Norman E. Lepor, MD, FACC, FAHA, FSCAI, past president of the California chapter of the American College of Cardiology, clinical professor of medicine at UCLA Geffen more
NCD Alliance and Resolve to Save Lives partner to eliminate industrially-produced trans-fatty acids
September 24 ,2018
Overview:The NCD Alliance (NCDA) has teamed up with Resolve to Save Lives to implement actions in support of the World Health Organization’s (WHO) REPLACE action package, a step-by-step guide for the elimination of industrially-produced trans-fat from the global food supply. Read the full article on the NCDA website The post NCD Alliance and Resolve to Save Lives partner to eliminate industrially-produced trans-fatty acids appeared first on World Heart Federation. more
Height may predict risk for varicose veins
September 24 ,2018
Overview:Nicholas J. LeeperGenes that determine height may also play a role in the formation of varicose veins, with taller people at greater risk for developing the condition, according to a study published in Circulation.“This study is the largest study ever conducted aimed at identifying the root causes of varicose vein disease, including data on almost half a million individuals,” Nicholas J. Leeper, MD, associate professor of cardiovascular medicine and vascular surgery and chief of vascular medicine at Stanford University, told Cardiology Today. “It included a large genetic more
WHF Cholesterol Roadmap presented at the Latin American Cholesterol Summit in Mexico
September 24 ,2018
Overview:On the 19-20 September, the Latin American Cholesterol Summit (Cumbre Latinoamericana del Colesterol) took place in Mexico City. As part of this event, World Heart Federation (WHF) member iHHub organized the WHF Cholesterol roadmap adoption for Mexico. The keynote speech was delivered by our CEO Jean-Luc Eiselé and Dr Enrique Morales Villegas from the Mexican […] The post WHF Cholesterol Roadmap presented at the Latin American Cholesterol Summit in Mexico appeared first on World Heart Federation. more
Patients with undiagnosed hypertension often have no history of CVD, diabetes
September 24 ,2018
Overview:Patients with undiagnosed hypertension typically had no other CVD or diabetes, according to findings recently published in Family Practice.“A primary care challenge is to identify potential factors that are associated with a higher risk of having undiagnosed hypertension among individuals meeting hypertension criteria,” Kénora Chau, MD, of the département de médecine Générale at the Université de Lorraine in France and colleagues wrote.“The knowledge of the risk patterns associated with these factors may be useful for primary care more
REDUCE-FMR: Regurgitant volume reduced with device during mitral annuloplasty in HF
September 24 ,2018
Overview:SAN DIEGO — Patients with HF and functional mitral regurgitation who received a device during transcatheter indirect mitral annuloplasty had a reduction in regurgitant volume at 1 year, according to data from the REDUCE-FMR trial presented at TCT 2018.The reduction was seen in both the implanted and intention-to-treat patient populations.Safety was similar in patients assigned the device (Carillon Mitral Contour System, Cardiac Dimensions) and the sham control.“From a heart failure perspective and from an implanter’s perspective, the REDUCE-FMR trial has shown that a more
SOLVE-TAVI: Valves, anesthesia strategies confer similar outcomes in symptomatic aortic stenosis
September 23 ,2018
Overview:SAN DIEGO — A self-expanding valve was equivalent to a balloon-expandable valve for 30-day outcomes in patients with symptomatic aortic stenosis who underwent transfemoral transcatheter aortic valve replacement, according to data from the SOLVE-TAVI trial presented at TCT 2018.In addition, local and general anesthesia strategies during TAVR resulted in similar outcomes, according to the study.Patients assigned the balloon expandable heart valve (Sapien 3, Edwards Lifesciences) may have resulted in higher stroke rates compared with those assigned the self-expanding valve (CoreValve more
COAPT: MitraClip reduces hospitalization, mortality in HF, mitral regurgitation
September 23 ,2018
Overview:SAN DIEGO — Patients with HF with moderate to severe or severe functional mitral regurgitation who underwent transcatheter mitral valve repair reduced the risk for HF hospitalization and mortality compared with patients treated with medical therapy alone, according to 2-year data from the COAPT trial presented at TCT 2018.Patients who underwent the procedure with the transcatheter device (MitraClip, Abbott) also had improved exercise tolerance and quality of life.The findings are contrary to the MITRA-FR trial, in which, as Cardiology Today’s Intervention previously reported, more
SORT OUT IX: Biolimus-eluting stent noninferior to SES
September 22 ,2018
Overview:Lisette Okkels JensenSAN DIEGO — A polymer-free biolimus-eluting stent was noninferior to a biodegradable polymer sirolimus-eluting stent in patients who underwent PCI, according to data presented at TCT 2018.Lisette Okkels Jensen, MD, DMSci, PhD, of Odense University Hospital in Odense, Denmark, and colleagues analyzed data from 3,151 patients treated with PCI who were enrolled between December 2015 to April 2017.Patients were assigned a polymer-free biolimus-eluting stent (BioFreedom, Biosensors; n = 1,572) or a biodegradable polymer sirolimus-eluting stent (Orsiro, Biotronik; n = more
LEADERS FREE II: Superior safety, efficacy in drug-coated stent vs. BMS
September 22 ,2018
Overview:SAN DIEGO — A drug-coated stent had superior safety and efficacy regarding death, MI and target lesion revascularization at 1 year compared with a bare-metal stent, according to data presented at TCT 2018.The drug-coated stent (BioFreedom, Biosensors International) assessed in this trial was part of the pivotal trial to support the device registration decision in the United States, Mitchell W. Krucoff, MD, professor of medicine at Duke University School of Medicine and member in the Duke Clinical Research Institute, said during the press conference.“This stent is commercially more
WHF welcomes a new Tobacco Expert Group
September 13 ,2018
Overview:Following a call for applications in early 2018, we are very excited to announce that eight distinguished advocacy and tobacco control experts from around the world were approved by the WHF Board on the 30th of June. The Group will be chaired by Floris Italianer, who said, “As the chair of the WHF Tobacco Expert […] The post WHF welcomes a new Tobacco Expert Group appeared first on World Heart Federation. more
WikiCardio
September 09 ,2018
Overview: WikiCardio es una excelente iniciativa de nuestro miembro la Sociedad Argentina de Cardiología. Es un sitio gratuito con información sobre temas cardiológicos en español desarrollado por expertos de la Sociedad Argentina de Cardiología para pacientes y sus familiares. Organizado como una enciclopedia online de términos médicos, WikiCardio contiene información confiable, sintética y comprensible sobre […] The post WikiCardio appeared first on World Heart Federation. more
The Heart & Stroke Foundation of South Africa celebrates Heart Awareness Month
September 06 ,2018
Overview:My Heart, Your Heart: Heart Awareness Month 2018 The Heart and Stroke Foundation South Africa (HSFSA) is embracing the World Heart Federation theme: My Heart Your Heart and going a mile further too by extending the theme for South Africa to: My Heart Your Heart and the Hearts of all South Africans. Their theme and […] The post The Heart & Stroke Foundation of South Africa celebrates Heart Awareness Month appeared first on World Heart Federation. more
Just 3 weeks to go until the UN High-Level Meeting on NCDs
September 05 ,2018
Overview:As we all know, the countdown has begun to the 3rd UN High-Level Meeting on NCDs. It’s time to get really, really busy. Here are a few suggestions from our partners at the NCD Alliance: Plan something locally for the Global Week for Action on NCDs (3-9 September), then share it globally; Become, or nominate, an NCD Champion, […] The post Just 3 weeks to go until the UN High-Level Meeting on NCDs appeared first on World Heart Federation. more
The Canadian Cardiovascular Society (CCS) launches a new e-Guidelines website
September 05 ,2018
Overview:The Canadian Cardiovascular Society (CCS), member of the World Heart Federation (WHF), is pleased to announce their new e-Guidelines website. This website allows users to quickly browse, search and filter CCS’s Heart Failure and Atrial Fibrillation guidelines. Access the CCS e-Guidelines website The post The Canadian Cardiovascular Society (CCS) launches a new e-Guidelines website appeared first on World Heart Federation. more
The British Heart Foundation launches the Big Beat Challenge at the European Society of Cardiology Congress
September 04 ,2018
Overview:A £30 million research award for the world’s greatest minds to tackle the world’s biggest killers The British Heart Foundation (BHF), a World Heart Federation (WHF) member partner, recently launched a major international initiative – the Big Beat Challenge: a single research award of up to £30 million over 5 years. The aim is to […] The post The British Heart Foundation launches the Big Beat Challenge at the European Society of Cardiology Congress appeared first on World Heart Federation. more
World Congress of Cardiology 2019 to be held in Paris together with European Society of Cardiology
September 03 ,2018
Overview:The World Heart Federation is pleased to announce that our next congress, following WCC 2018 in Dubai, will be held in Paris in 2019, in conjunction with our member, the European Society of Cardiology (ESC). This will be the first World Congress of Cardiology under a new model, which will see the congress taking place […] The post World Congress of Cardiology 2019 to be held in Paris together with European Society of Cardiology appeared first on World Heart Federation. more
WHF to attend the WHO Executive Board meeting in January 2017
January 23 ,2017
Overview:From 23 January to 01 February 2017, the World Health Organization(WHO) will host the 140th session. From 23 January to 01 February 2017, the World Health Organization(WHO) will host the 140th session. From 23 January to 01 February 2017, the World Health Organization(WHO) will host the 140th session. From 23 January to 01 February 2017, […] more