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International Society of Cardiovascular Pharmacotherapy Latest News

Posted on November 2, 2026

Testosterone therapy may lead to CVD risk in postmenopausal women

Testosterone therapy may be associated with a higher risk for CVD for postmenopausal women, according to research presented at The Menopause Society’s annual meeting. Xuezhi (Daniel) Jiang, MD, PhD, a professor at Drexel University College of Medicine’s department of obstetrics and gynecology, and colleagues wrote that they conducted a cohort study to analyze the connection between testosterone therapy and CVD in postmenopausal women. “Cardiovascular disease remains the number one killer of women, and studies like this are important as long-term safety data on testosterone use in women are

Posted on November 2, 2026

Acute MI in cancer potentially underdiagnosed, undertreated

Patients with cancer may have lower rates of acute MI but higher rates of CV death vs. the general public; however, revascularization for MI reduces risk for CV death vs. medical treatment alone, a speaker reported. Researchers posited that patients with cancer who experience an acute MI may be underdiagnosed and undertreated due to a healthcare disparity, according to data presented at the TCT Scientific Symposium and simultaneously published in JACC: Asia. “Patients with cancer are inherently at increased risk of coronary atherosclerosis and arterial thrombosis associated with

Posted on November 2, 2026

Q&A: Women now make up most of primary care DOs

LAS VEGAS — Women account for most DOs practicing primary care for the first time ever, a recent report from the American Osteopathic Association, or AOA, shows. According to the 2026 Osteopathic Medical Profession Report, women account for 50.2% of primary care DOs overall — up from 49.6% last year — and 55.4% of primary care DOs aged younger than 35 years. Additionally, the number of women DOs younger than age 45 years surpassed 50,000 for the first time, an AOA press release said. “As more women choose osteopathic medicine and primary care, patients benefit from a broader range of

Posted on November 2, 2026

AI tools often fail to identify validated BP devices

AI search tools did not always correctly identify the validation status of home BP monitors, according to an abstract presented at the American Heart Association’s Hypertension Scientific Sessions. “People may unknowingly think a device is validated based on the AI tool’s inaccurate responses,” Anna Soriano, MD, third-year internal medicine resident at the University of Montreal, said in a press release. “Using that device may result in inaccurate blood pressure readings, which could lead to an inappropriate diagnosis or treatment decisions.” The American Heart Association recently released a

Posted on October 30, 2026

Judge blocks CMS’ medical frailty rule

A federal judge struck down a CMS rule requiring Medicaid beneficiaries with qualifying medical conditions to prove they cannot meet new work requirements. The order does not overturn the broader Medicaid work requirements enacted under H.R.1, or the One Big Beautiful Bill. Starting Jan. 1, certain Medicaid beneficiaries aged 19 to 64 years will be required to engage in qualifying activities — employment, community service or some work programs — for 80 hours per month, or make at least $580 monthly (the minimum wage multiplied by 80 hours), “or be enrolled in educational program for at least

Posted on October 30, 2026

HHS updates labels for three estradiol transdermal patches

HHS approved updated labels for three additional menopausal hormone therapy products today. The agency took action on the products — estradiol transdermal patches which come from two applicants — through the FDA, according to a press release from HHS. The FDA approved labeling changes clarifying the risk-benefit associations for six menopausal hormone therapy (MHT) products in February. The action today “expands this effort by approving the removal of the same outdated risk statements” for breast cancer, CVD and probable dementia from the black box warnings for the three patches. When

Posted on October 30, 2026

Solutions emerging for resistant, uncontrolled hypertension

BOSTON — Too many adults have uncontrolled or resistant hypertension, but more solutions are available now or will be soon, a speaker said at the Cardiometabolic Health Congress. “If your patient needs four blood pressure medications to be controlled, they have resistant hypertension,” Naomi D.L. Fisher, MD, endocrinologist and director of hypertension services at Brigham and Women’s Hospital and associate professor of medicine at Harvard Medical School, said during a presentation. “Why do we care? Because this group of patients carries the very highest cardiovascular risk. This is the No. 1

Posted on October 30, 2026

Healthy eating may help cancer survivors live longer

Healthy eating may help cancer survivors live longer and lower their risk for ischemic heart disease, heart failure or stroke, according to data published in JACC: Advances. Implementing or maintaining a high-quality, heart-healthy diet such as the Mediterranean, Dietary Approaches to Stop Hypertension (DASH) or Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) diet after a cancer diagnosis may have cardioprotective benefit and enhance overall survival, researchers reported. In addition, the reduced risk for CV events was not observed with high intake of a healthy

Posted on October 30, 2026

Simple steps to improve environmental sustainability in the clinic

Dermatology clinics contribute to climate change, but targeting supply chain practices can decrease their environmental impact, according to a study published in the International Journal of Dermatology. “A substantial amount of evidence indicates that climate change and pollution broadly harm health and specifically play a role in many skin diseases, often disproportionately affecting our most vulnerable and marginalized patients,” Eva Rawlings Parker, MD, DTMH, FAAD, assistant professor of dermatology at Vanderbilt University Medical Center, told Healio. “Healthcare is a notable part of that

Posted on October 30, 2026

AI model finds cardiogenic shock risk before hypotension onset

PHOENIX — Using admission data, a machine learning model detected patients with acute coronary syndrome at high-risk for cardiogenic shock 1.8 hours before the onset of hypotension, according to data presented at the CHEST Annual Meeting. “For the clinician at the bedside, the practical value [of the model] is earlier situational awareness,” Sadhu Reddy, MD, internal medicine resident at Northwestern Medicine McHenry Hospital, told Healio. “Embedded in an acute coronary syndrome (ACS) care pathway, a model like this could surface a risk estimate at the moment of admission — before the blood

Posted on October 29, 2026

HHS further loosens restrictions for several peptides

HHS has taken action to expand access to six peptides that were key in a controversial meeting this summer. The interim enforcement policy states that, based on the Pharmacy Compounding Advisory Committee (PCAC) meeting that took place in July, “HHS believes that there is significant interest in the use of these peptides in compounding.” So, in an effort “to expand and improve patient access while FDA reviews these substances,” HHS will not take action against physicians, state-licensed pharmacies or federal facilities compounding a drug using the following bulk drug substances on the 503A

Posted on October 29, 2026

New framework for managing women’s heart health

Societies issued a three-part publication series aimed at improving heart health outcomes for women through a life course approach, tying CVD risk to specific female life stages, which could enable earlier intervention. The series also aimed to address the underrepresentation of women in science and the fragmented nature of current women’s CV care. Sadiya S. Khan, MD, MSc, FAHA, Magerstadt Professor of Cardiovascular Epidemiology and associate professor of cardiology and preventive medicine at Northwestern University Feinberg School of Medicine, said the work focuses on moving away from

Posted on October 29, 2026

Aspirin does not reduce risks for major CV events vs. usual care in CKD

DENVER — Low-dose aspirin did not significantly reduce risks for major CV events vs. usual care among patients with chronic kidney disease, according to data presented at ASN Kidney Week. “We’re not in a place where we should be offering aspirin for primary prevention at this stage,” Hugh Gallagher, MBBS, MS, MSc, PhD, consultant nephrologist at Epsom and St Helier University Hospitals NHS Trust, told Healio. The primary interventions for preventing CV events in CKD are limited to lipid-lowering therapies and SGLT2 inhibitors, according to Gallagher. Aspirin may provide CV benefits or risks

Posted on October 29, 2026

Obesity impact on women can be related to hormonal changes

BOSTON — Obesity has a different impact on women than it does on men, and women can benefit from weight loss at any stage of life, a speaker said at the Cardiometabolic Health Congress Women’s Cardiometabolic Health and Wellness Masterclass. “Obesity is a disease. It affects women during the periods of hormonal change more because of the way those hormone changes interact with the hormones that go to the brain and regulate energy balance,” Healio | Endocrine Today Editorial Board Member Caroline M. Apovian, MD, FACN, FACP, FTOS, DABOM, professor of medicine at Harvard Medical School and

Posted on October 29, 2026

CagriSema lowers weight for women across reproductive lifespan

Once-weekly CagriSema reduced weight by 25% at 68 weeks for women with overweight or obesity, and weight loss was observed among women across all reproductive stages, according to data from two posters. As Healio previously reported, adults receiving a once-weekly combination of cagrilintide 2.4 mg and semaglutide 2.4 mg (Novo Nordisk) in the REDEFINE 1 trial lost 20.4% of their body weight at 68 weeks compared with a 3% weight loss for those receiving placebo, according to the treatment policy estimand. In post hoc analyses presented at the Annual Meeting of The Menopause Society, researchers

Posted on October 28, 2026

‘They are not going away’: Why peptides are a must-know for ED clinicians

LAS VEGAS — Emergency clinicians must familiarize themselves with the various types of peptides and their potential adverse effects, according to a speaker at OMED. Peptide popularity has boomed in recent years, but for many peptides, little is known about the long-term effects. Healio spoke with Kenneth L. Frye Jr., DO, a physician at TeamHealth, about which peptides ED clinicians frequently encounter, what to look for in patients who use unapproved peptides and more. Healio: What are some of the challenges clinicians face when diagnosing peptide-related visits? Frye: I don’t think physicians

Posted on October 28, 2026

CDC deputy director steps down after 4 months

Jennifer A. Shuford, MD, MPH, resigned as the CDC’s deputy director and chief medical officer after spending just 4 months at the agency. Shuford said she was leaving to spend more time with her family. “I am so thankful to President Trump and Secretary Kennedy for giving me the opportunity to help lead CDC,” she said in a statement provided to Healio. “It has been an amazing experience, and I will be forever grateful for it.” The Washington Post first reported Shuford’s departure. Two anonymous sources told the Post that disagreements over the Trump administration’s vaccine policies factored

Posted on October 28, 2026

Speaker: Time to end the ‘diet battles’

BOSTON — The “diet battles” are unhelpful and people should focus on eating healthy foods regardless of what diet they belong to, according to a speaker at the Cardiometabolic Health Congress. “We’re inundated with news, not just in the lay press, but also the scientific press, about this diet vs. that diet,” Lawrence J. Appel, MD, MPH, professor in the Welch Center for Prevention, Epidemiology and Clinical Research at Johns Hopkins University, said during a presentation. “Earlier this year, we published a paper, an update to dietary guidance. And in

Posted on October 28, 2026

WWE athletes’ hearts normal

Elite athletes from World Wrestling Entertainment experience normal cardiac remodeling associated with intense resistance training, but sex differences were evident, researchers reported. Some men experienced concentric cardiac remodeling, but did not have pathological hypertrophy, whereas women had larger left ventricular dimensions, according to the results of a study evaluating changes in cardiac structure and function among elite wrestlers published in the Journal of the American Heart Association. “This study provides novel insights into the cardiovascular phenotype of elite

Posted on October 27, 2026

Obesity and women’s gynecologic and reproductive health: What clinicians should know

Women’s reproductive and gynecologic health is influenced by a combination of hormonal, metabolic, environmental and lifestyle factors. Obesity plays an important part in that relationship, affecting reproductive health across the lifespan, from menstrual health and fertility to pregnancy and menopause. For clinicians, recognizing these connections can help support earlier diagnosis, more comprehensive treatment and better patient outcomes. At the same time, obesity should never become the sole explanation for a patient’s symptoms. Effective care requires looking at the whole patient,

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