Statin’ the source of that pain: Pharmacogenomics As A Preemptive Tool

Live webinar on Monday 8th July 2024 @13.00-14.00 BST

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And we are back with our third session of 2024! Join us for an insightful 1-hour LIVE webinar on pharmacogenomics!

Cardiovascular disease is the most important non-communicable disease in the over-burdened healthcare landscape all over the world. Statins are one of the most highly prescribed classes of medicines globally, owing to their high efficacy in attaining low-density lipoprotein cholesterol (LDL-C) goals and thus effectively reducing onset and recurrence of cardiovascular disease. However, Statin-Associated Myopathies (SAM) have been reported to afflict up to 1/3 of all patients receiving statins, and possibly one of the biggest contributors to statin non-adherence. Unfortunately, the nocebo effect, made famous by the SAMSON trial, is rife and causes many patients to stop their statins without first considering the benefits that LDL-C lowering could confer. Genetic polymorphisms in SLCO1B1 and ABCG2 have emerged as important considerations when trying to pre-empt SAM. In this session, the experts will take you through scenarios which known information on SLCO1B1 and ABCG2 would be useful in averting non-adherence to statins, and also to give confidence to the prescriber that the pain in the thighs is unlikely a harbinger of rhabdomyolysis.

Don’t miss this opportunity to gain valuable insights from leading experts in the field.

What we will cover in this exciting live session:
• A deep dive into the scientific background of statin pharmacogenomics and its applications.
• Review of the disposition of statins and their metabolites.
• What does the SLCO1B1 and ABCG2 polymorphisms lead to.
• What clinicians should know about when interpreting and using lab reports of polymorphism, including how variants of unknown origin should be handled in clinical practice.

The LIVE broadcast will be offered free of charge. On-demand recordings will be exclusive to ISCP Full & Associate members only, through ISCP website.

if you wish to join ISCP please visit our membership section for details on membership options: www.membership.iscpcardio.org