Anti-Inflammatory Therapy with Canakinumab for the Prevention and Management of Diabetes

May 22, 2018

Overview : Trial Reference Everett BM, Donath MY, Pradhan AD, Thuren T, Pais P, Nicolau JC, Glynn RJ, Libby P, Ridker PM. Anti-Inflammatory Therapy with Canakinumab for the Prevention and Management of Diabetes.  J Am Coll Cardiol. 2018 Mar 3. pii: S0735-1097(18)33483-1. doi: 10.1016/j.jacc.2018.03.002.... more

THE FREEDOM TRIAL: ” Future Revascularisation Evaluation in patients with diabetes mellitus: Optimal management of multivessel disease”

Jul 17, 2014

Overview : FREEDOM was a 5-year superiority trial. Researchers randomly assigned 1,900 patients (mean age, 63 years; 29% women) with diabetes and multivessel CAD to CABG or PCI with a DES at 140 centers throughout the world between 2005 and 2010. Patients... more

EXAMINE (EXamination of CArdiovascular OutcoMes: AlogliptIN vs. Standard of CarE in Patients with Type 2 Diabetes Mellitus and Acute Coronary Syndrome)

Jul 17, 2014

Overview : We have selected EXAMINE because is one of the largest triasl analizing cardiovascular outcomes and safety with a new group of antidiabetic drugs. The main results showed the primary endpoint of non-inferiority compared to placebo in addition to standard of... more