Individualisation of Antiplatelet Therapy with CY2C19

Presenter: Doreen Tan

Nov 01, 2021

Overview : Why is CYP2C19 polymorphism such a big deal? Clopidogrel requires a two-step activation into the active moiety. CYP2C19 is involved in both steps… more

Single Nucleotide Polymorphisms (SNPs): Role in Precision Medicine

Presenter: Ms Png Wan Yu , Prof Tai E Shyong

Nov 01, 2021

Overview : Single nucleotide polymorphisms, which are called SNPs, and their role in precision medicine. The first of three CLAPs on pharmacogenomics in pharmacotherapy. more

Pharmacogenomics in Cardiology: Focus on Warfarin Genotyping

Presenter: Mr Kim Ji Heon , Prof Goh Boon Cher

Nov 01, 2021

Overview : Pharmacogenomics in cardiology with a focus on warfarin genotyping. Warfarin is most susceptible to genetic polymorphisms that encode for CYP2C9 and VKORC1 enzymes… more

Is Age a Comorbidity which Compels Dose Adjustment with DOACs?

Presenter: Dr Koji Hasegawa , Mr Marvin Sim

Oct 04, 2021

Overview : We will look at the available evidence for the following DOACs that require adjustments due to age. They Apixaban, Dabigatran and Edoxaban. more

Iron Therapy in Heart Failure

Presenter: Dr Louis Teo , Ms Thng Shu Hui

Apr 23, 2021

Overview : Iron deficiency is a common co-morbidity among heart failure patients, with a reported prevalence of between 30% to 50%.Patients can be iron deficient without being anaemic. Iron deficiency diminishes exercise capacity and is associated with poor quality of life s... more

SGLT2 Inhibitors as Leaders in HFrEF?

Presenter: Gheorghe-Andrei Dan , Oh Jing Wen

Apr 22, 2021

Overview : Professor G. Andrei-Dann, Ms Oh Jing Wen and Ms Claire Lew present our two-part overview of SGLT2 Inhibitors as Leaders in HFrEF. Part of our Clap in 60 Seconds series of bite-sized topics. more

One-month Dual Anti-Platelet Therapy (DAPT) in Patients with HBR Undergoing PCI

Presenter: Mark Y Chan

Feb 08, 2021

Overview : Dr Mark Y Chan presents a short introduction to one-month dual anti-platelet therapy (DAPT) in patients with high bleeding risk (HBR) undergoing percutaneous coronary intervention (PCI). more

Transcatheter Renal Denervation

Presenter: Dr Ong Tiong Kiam

Feb 08, 2021

Overview : The renal sympathetic system plays a central role in the pathophysiology of hypertension. Ablation of renal nerves offers patients a one-off treatment with sustainable, long-term benefits…. Dr TK Ong presents a short introduction to transcatheter renal denervation including the Spyral... more

How do I choose Oral Anticoagulants (OACs) in Renal or Liver Impairment?

Presenter: Doreen Tan Su-Yin

Nov 04, 2020

Overview : Bite-sized videos covering ‘Dosing DOACs in Renal Impairment’ and ‘Renal Function & Drug Dosing’ – together with a handy Cheat Sheet including DOAC dosing tables. more

Heart Failure & Atrial Fibrillation: A Deadly Alliance

Presenter:  Gheorghe-Andrei Dan

Oct 20, 2020

Overview : A short talk about the deadly alliance between heart failure and atrial fibrillation. Both heart failure and atrial fibrillation increase with age; nearly half of all patients with heart failure have atrial fibrillation and more than half of patients with... more