THE FREEDOM TRIAL: ” Future Revascularisation Evaluation in patients with diabetes mellitus: Optimal management of multivessel disease”

Jul 17, 2014

Overview : FREEDOM was a 5-year superiority trial. Researchers randomly assigned 1,900 patients (mean age, 63 years; 29% women) with diabetes and multivessel CAD to CABG or PCI with a DES at 140 centers throughout the world between 2005 and 2010. Patients... more

STREAM-Strategic Reperfusion With Tenecteplase and Antithrombotic Treatment Early After Myocardial Infarction

Jul 17, 2014

Overview : This trial confirmed that fibrinolysis with tenecteplase and contemporary antithrombotic therapy given before transport to a PCI-capable hospital, coupled with timely coronary angiography, is as effective as primary PCI in STEMI patients presenting within 3 hours of symptom onset who... more

CHAMPION-PHOENIX: A Clinical Trial Comparing Cangrelor to Clopidogrel Standard of Care Therapy in Subjects Who Require Percutaneous Coronary Intervention

Jul 17, 2014

Overview : The study randomized over 11,000 patients and the result showed that intravenous cangrelor cut the risk for periprocedural complications at all kinds of PCI compared with taking a pill of clopidogrel. Cangrelor's benefit of a 22% drop in a composite... more