Caloric intake may be more important for weight loss than meal timing, study suggests
April 19 ,2024
Overview:BOSTON — Time-restricted eating did not result in more weight loss vs. a usual eating pattern, suggesting that overall caloric intake may have a larger effect on weight loss than meal timing, researchers reported.The findings were presented during the plenary session at the ACP Internal Medicine Meeting and simultaneously published in Annals of Internal Medicine.“We feel that clinicians can counsel their patients that [time-restricted eating (TRE)] may help them to lose weight, but likely because of a decrease in caloric intake,” Nisa M. Maruthur, MD, MHS, FACP, an associate more
Pregnancy CVD risk calculator may underestimate odds for events among low-resource women
April 19 ,2024
Overview:ATLANTA — Pregnant women with fewer economic resources may still be at elevated risk for CVD despite a low score on a CVD risk calculator, researchers reported.The CARPREG II risk index was created to better predict prognosis during pregnancies with heart disease, as 15% to 30% of CV complications can result in mortality, Kimberly R. Ding, MD, a resident physician at Harbor-UCLA Medical Center, said during a moderated poster presentation at the American College of Cardiology Scientific Session.“There is a paucity of data and cardio-obstetrics is still a developing area, so we more
Acoramidis may improve cardiac mass, function in transthyretin amyloid cardiomyopathy
April 19 ,2024
Overview:ATLANTA — Data from a small substudy with cardiac MRI suggest acoramidis may improve both cardiac mass and function for adults with symptomatic transthyretin amyloid cardiomyopathy, building on previous positive data, researchers reported.The findings were presented at the American College of Cardiology Scientific Session.As Healio previously reported, data from the phase 3 ATTRibute-CM trial showed that acoramidis (BridgeBio), an investigational, next-generation, small molecule stabilizer of transthyretin (TTR), demonstrated consistent benefits on survival, hospitalization and other more
Topol: AI-fueled ‘keyboard liberation’ will improve the medical encounter
April 18 ,2024
Overview:BOSTON — “We should be embracing [AI] and trying to make this a priority to get this right, because I don’t know any alternative to get us out of this frustration right now outside of this technology,” Eric Topol, MD, said.“The opportunity is vast ... and we must eke out the advantages,” Topol, who is the Founder and Director of the Scripps Research Translational Institute, said during the ACP Internal Medicine Meeting keynote.AI has already shown promise in medicine, particularly in specialties with advanced diagnostics and screening.“Every type of more
Survival rates, outcomes favorable for those given ECMO with neurosurgical intervention
April 18 ,2024
Overview:DENVER —Extracorporeal membrane oxygenation therapy led to favorable survival and neurologic outcomes for patients who required neurosurgical intervention, according to a poster at the American Academy of Neurology annual meeting.“We wanted to look at patients that underwent neurosurgical interventions either before or during [extracorporeal membrane oxygenation], as it’s usually a contraindication,” Samantha Marie Helmy, BA, from the University of Rochester School of Medicine and Dentistry, told Healio. “Helmy and colleagues conducted a retrospective chart more
Q&A: Obesity Medicine 2024 is ‘a pinnacle moment,’ featuring latest updates in treatment
April 18 ,2024
Overview:Hundreds of clinicians will gather in Denver next week to discuss the latest treatment strategies and evidence-based approaches to obesity management.The Obesity Medicine Association’s (OMA’s) 2024 Conference kicks off April 24-28, featuring a wide range of speakers and topics in the field of obesity medicine. The meeting is now the OMA’s largest event of the year, followed by a more narrowly focused summit on obesity and women’s health in the fall.Healio will be on site providing live coverage of this year's conference, so be sure to check back regularly for updates. more
Gene therapy to treat congestive heart failure gains FDA fast track designation
April 18 ,2024
Overview:Bayer AG and its subsidiary Asklepios BioPharmaceutical announced the FDA granted fast track designation for its investigational gene therapy for the treatment of congestive heart failure.The fast track designation is granted to therapies with the potential to fill unmet needs of patients with serious medical conditions. It includes the ability for the developer to have more frequent interactions with the agency, and potentially future accelerated priority review and accelerated approval.The investigational therapy (AB-1002, also known as NAN-101) is a one-time gene therapy administered to more
Heart failure a more common complication than stroke in people with atrial fibrillation
April 18 ,2024
Overview:In a large Danish cohort, heart failure was a more significant CV complication than stroke after diagnosis of atrial fibrillation, which became more common over 20 years.“To our knowledge, the temporal trends in lifetime risks of atrial fibrillation and complications after atrial fibrillation have not been reported previously,” Nicklas Vinter, MD, PhD, of the Danish Center for Health Services Research at Aalborg University in Denmark, and colleagues wrote in The BMJ. “Among patients with newly diagnosed atrial fibrillation, heart failure was the most frequent complication more
Q&A: First responders need to be trained in how women present with heart attack
April 18 ,2024
Overview:Too often, heart attack signals are missed or misdiagnosed in women, not just by patients and providers, but by first responders as well.When Jolie Busch, a member of the board at the Women’s Cardiovascular Health Center at UCLA and a former emergency medical technician (EMT), was serving as an emergency department volunteer, she noticed an unexpectedly high number of young women presenting with symptoms that turned out to be heart attacks but were often not initially diagnosed as such. Realizing that the best chance of a prompt correct diagnosis was through better education of first more
Am I allowed to be quiet? Looking through the lens of an introvert in medicine
April 17 ,2024
Overview:Ever since my third-year clinical rotations in medical school, I can usually predict what will be written about me in my evaluations before seeing them.The phrases “be more outspoken” and “try not to be so quiet” were copied and pasted in every form. There was usually nothing written about improvement in my knowledge or patient communication. When I started residency, I thought that I would never see those comments again, but they quickly came back to haunt me in my first evaluation as an intern. Under things to improve on, there were the words “be more outspoken.” more
Tirzepatide improves sleep apnea symptoms for adults with OSA plus obesity
April 17 ,2024
Overview:Adults with moderate to severe obstructive sleep apnea and obesity had reductions in sleep apnea severity at 1 year with 10 mg or 15 mg of tirzepatide, according to topline results from two phase 3 trials.As Healio previously reported, tirzepatide (Zepbound, Eli Lilly) was approved by the FDA for chronic weight management among adults with obesity in November 2023. Topline results from the SURMOUNT-OSA trials showed tirzepatide may have benefit beyond body weight reductions, as participants receiving the agent had greater reductions in apnea-hypopnea index (AHI) than placebo. AHI is a measure more
E-cigarette use could raise heart failure risk up to 19%
April 17 ,2024
Overview:ATLANTA — Individuals with a history of e-cigarette use may have increased risk for incident heart failure, regardless of concomitant cigarette, cigar, hookah or smokeless cigarette use, a speaker reported.“More and more studies are linking e-cigarettes to harmful effects and finding that it might not be as safe as previously thought,” Yakubu Bene-Alhasan, MD, resident physician at MedStar Health in Baltimore, said in a press release. “The difference we saw was substantial. It’s worth considering the consequences to your health, especially with regard to heart health.” more
Arrhythmias tied to poorer survival in adults with congenital heart disease
April 17 ,2024
Overview:Arrhythmia disorders in patients with adult congenital heart disease may significantly contribute to hospitalization and mortality risk, according to data published in the Journal of the American Heart Association.“Our findings highlight the need for ongoing, lifelong, clinical follow-up for people with congenital heart disease,” Nili Schamroth-Pravda, MBBCh, cardiologist at the Rabin Medical Center in Petah Tikva, Israel, said in a press release. “With the improvement of medical and surgical techniques, the number of patients with congenital heart disease reaching adulthood more
ESC scoring tool predicts survival in SSc-associated pulmonary arterial hypertension
April 17 ,2024
Overview:The 2022 European Society of Cardiology risk assessment tool, when applied at baseline and follow-up, can accurately predict survival in patients with systemic sclerosis-associated pulmonary arterial hypertension, according to data.“In 2015, the European Society of Cardiology (ESC) and European Respiratory Society (ERS) guidelines recommended a multidimensional risk assessment tool to guide treatment decisions and prognostication in pulmonary arterial hypertension (PAH),” Zoe Brown, MBBS, FRACP, of St. Vincent’s Hospital in Melbourne, Australia, and colleagues wrote in more
Remote postpartum BP monitoring could address gaps in care, cut heart disease risk
April 16 ,2024
Overview:ATLANTA — Implementing a remote postpartum BP monitoring program for women with persistent hypertension after delivery was shown to be feasible and linked to higher rates of primary care provider visits and BP control, researchers reported.Hypertensive disorders of pregnancy are associated with high rates of postpartum hypertension, and data show that half of women have persistent hypertension at 6 weeks postpartum, Anisha R. Reddy, MD, a medical resident at University of Pittsburgh Medical Center, said during a moderated poster theater at the American College of Cardiology Scientific more
Coronary sinus reducer improves symptoms, quality of life for patients with severe CAD
April 16 ,2024
Overview:ATLANTA — Use of a coronary sinus reducer improved chest pain symptoms and quality of life for patients with significant coronary artery disease, despite not improving myocardial blood flow, a speaker reported.The results of the randomized, placebo-controlled ORBITA-COSMIC trial were presented at the American College of Cardiology Scientific Session and simultaneously published in The Lancet.“The coronary sinus reducer is the only device that is postulated to improve angina from the venous circulation,” Rasha Al-Lamee, MBBS, PhD, a clinical academic interventional cardiology more
High risk for cardiovascular disease in patients with alpha-1 antitrypsin deficiency
April 16 ,2024
Overview:Aortic stiffness, a known risk factor for cardiovascular disease, was raised among patients with alpha-1 antitrypsin deficiency vs. patients with COPD or healthy individuals, according to study results.“We have found that traditional cardiovascular disease risk factors, such as smoking, may not account for all cardiovascular disease risk in patients with the condition, alpha-1 antitrypsin deficiency,” Louise E. Crowley, MBChB, clinical research fellow and PhD researcher at University of Birmingham, told Healio. “This suggests that the everyday clinician should be cautious in more
‘Good friction:’ Experts share how artificial intelligence works in their office
April 15 ,2024
Overview:DENVER — Incorporating artificial intelligence into daily practice can benefit both providers and patients, according to experts here at the American Academy of Neurology annual meeting.In a panel discussion, Louis A. Tramontozzi, III, MD, a neurologist in private practice at North Shore Neurology in Massachusetts, detailed how his team has implemented several AI-related tools to improve provider and staff productivity and wellbeing, while generating cost savings and a positive impact on patient satisfaction.Tramontozzi’s practice, which consists of about nine providers, receives more
LVAD obstruction linked to 14 deaths; FDA designates recall as class I
April 15 ,2024
Overview:Abbott/Thoratec Corp. issued a recall of two of its left ventricular assist devices due to risk for obstruction from the long-term buildup of biological material during use.There have been 273 injuries and 14 deaths related to the issue, according to an alert from the FDA.The FDA has identified the recall of the LVADs (HeartMate II and HeartMate 3) as a class I recall, the most serious type of recall, as use of the devices may cause serious injury or death. The FDA stated this recall is a correction, not a product removal.Device obstruction, called extrinsic outflow graft obstruction, more
PCI may benefit patients with unblocked arteries but vulnerable plaque vs. medical therapy
April 15 ,2024
Overview:ATLANTA — Preventive PCI plus optimal medical therapy was superior to optimal medical therapy alone for patients with nonflow-limiting vulnerable coronary plaques, according to the results of the PREVENT trial.The patient population of 1,606 included those with coronary stenosis greater than 50% but negative fractional flow reserve ( 0.8) who had vulnerable plaque as determined by meeting at least two of the following criteria on intracoronary imaging: minimal lumen area of 4 mm2 or less, plaque burden greater than 70%, thin-capped fibroatheroma by OCT or radiofrequency IVUS or more
Hello world!
February 04 ,2021
Overview:Welcome to WordPress. This is your first post. Edit or delete it, then start writing! The post Hello world! appeared first on World Heart Federation. more
WHF to attend the WHO Executive Board meeting in January 2017
January 23 ,2017
Overview:From 23 January to 01 February 2017, the World Health Organization(WHO) will host the 140th session. From 23 January to 01 February 2017, the World Health Organization(WHO) will host the […] more